Department of Laboratory Medicine and Pathology

About Us

The Medical City Department of Laboratory Medicine and Pathology operates under the discipline of laboratory medicine and provides relevant information for the diagnosis, prevention or treatment of disease, impairment of personal care, and assessment of health.

The Laboratory, located at the Lower Ground Floor, is a fully equipped modern diagnostic facility offering a broad range of tests. It is staffed by clinical and anatomic pathologists, a clinical microbiologist/infectious disease specialist, a manager, supervisors, section heads, a competency specialist, staff medical technologists and administrative support personnel.

The Laboratory processes over two million laboratory procedures annually. It has extensive testing capabilities in the following areas: Chemistry, Hematology, Blood Bank and Transfusion Services, Clinical Microscopy, Histology/Cytology, Microbiology, Serology, Immunology/Special Chemistry and Molecular Biology. The Laboratory can also provide a vast majority of routine tests, as well as a variety of special procedures. Ninety nine percent of all testing is performed in-house. A home phlebotomy service is available for ambulatory and non-ambulatory patients.

Services

Blood Bank & Transfusion Services

Anti HIV (VCT)Test

Antibody Identification

Antibody Screening

Apheresis

A. Therapeutic Application

a. Cytapheresis

a.a. Leukopheresis

a.b. Platelet Reduction

a.c. Erythrocytapheresis

b.Therapeutic Plasma Exchange (TPE)/Plasmapheresis

B. Donor Application

a. Plateletpheresis

C. Dendritic Cell Collection (Stem Cell)

Blood Products:

A. Whole Blood

B. Packed RBC

C. Packed RBC, Washed

D. Platelet Concentrates

E. Fresh Frozen Plsama

F. Cryoprecipitates

G. Cryosupernates

Blood typing

A. Blood Grouping (ABO Grouping)

B. Rh typing

Coomb's Test(Direct/Indirect Antiglobulin Test)

Crossmatching/ Compatibility Testing Donor Screening

A. Anti-HIV (VCT)

B. Anti-HCV

C. HBsAg

D. Rapid Plasma Reagin/RPR

E. Rapid test For Malaria

Du Typing/Weak Antigen

Therapeutic Phlebotomy

Hematology & Coagulation

Absolute Count (Eosinophil, Neutrophil)

Activated Clotting Time

Activated Partial Thromboplastin (APTT)

Anti-thrombin III

Bleeding time and Clotting time (CT/BT)

CBC Profile (Hemoglobin, Hematocrit, WBC count, RBC count, Differential count, RBC morphology, Platelet and Red cell indices)

Cell Count of Body Fluids: Gross Exam. WBC, RBC, Differential Count

Clot Retraction Time (CRT)

D-Dimer

Dilute Russell Viper Venom Test (DRVVT)

Erythrocyte Osmotic Fragility Test (EOFT)

Erythrocyte Sedimentation Rate (ESR)

Factor V

Factor V Leiden

Factor VIII

Fibrin Degradation Products (FDP)

Fibrinogen

Hams Test/Acid-serum Test

Iron Staining

Kaolin Clotting Time (KCT) / PTT-LA

LAP/ Leucocyte Alkaline Phosphatase

Lupus Erythematosus Preparation

Malaria Antigen

Malarial Smear

PAS/Periodic Acid Schiff Staining

Peripheral Blood Smear

POX/ Peroxidase Staining

Platelet count

Protein C

Protein S

Prothrombin Time

Red Cell Indices (MCV,MCH,MCHC)

Reticulocyte Count

Semen Analysis: Volume, Color, Spermatozoa Count, % Abnormal Forms, Viscosity

Sugar Water Test

Clinical Miscroscopy & Parasitology

Acetone/ketones(Qualitative)

Apt’s test

Bence Jones Protein : Qualitative

Direct Flourescent Antibody (DFA)

Fecal Fat

Formalin Ether Concentration Test, Stool (FECT)

Free Hemoglobin ,Urine

Glucose, Urine

H-Pylori Antigen, Stool

Kato-Katz

Lactoferrin/ Leuko-Test

Microalbumin/Micral Test

Myoglobin

Occult Blood

Ph, Urine

Ph, Stool

Pregnancy Test (Urine HCG)

Rotavirus

Routine Fecalysis

Routine Urinalysis (Flow cytometry)

Scotch Tape Technique/ Perianal Fecal Debris Examination

Specific Gravity

Urine Cell Morphology

Urobilinogen / Erlich-tube test

Urine Reducing Sugar

Clinical Chemistry

Substrate

Albumin

Ammonia

Bicarbonate

Bilirubin : Total, Direct, Indirect

Calcium, Ionized

Calcium, Total

Calcium, Urine

Cholesterol, HDL

Cholesterol, LDL

Cholesterol, Total

Creatinine Clearance (24 hour Urine)

Creatinine, Blood

Creatinine, Urine

Cystatin C

Glucose, Challenge Test

Glucose, CSF

Glucose, Fasting

Glucose, Random

Glucose, Tolerance Test

Glucose, Two Hour Post Prandial

Glycomark

Glycosylated hemoglobin (HBA1c)

Iron Binding capacity, Unsaturated

Iron, Serum

Lactate

Magnesium, blood/urine

Phosphorus

Phosphorus, Urine

Protein, CSF

Protein, Total (A/G Ratio)

Triglycerides

Urea Nitrogen, 24hour Urine

Urea/ BUN

Uric Acid

Uric Acid, Urine

Enzymes

Acid Phosphatase (ACP)

Alanine Aminotransferase (ALT/SGPT)

Alkaline Phosphatase (ALP)

Amylase

Amylase, Urine

Aspartate Aminotransferase (AST/SGOT)

Creatinine Kinase (Total, CK-MB, CK-MM)

Homocysteine

Glucose-6-Phosphate Dehydrogenase (G6PD)

Glutamyltransferase (GGT)

Lactate

Lactate Dehydrogenase (LDH)

Lipase

Troponin T (Quantitative)

Troponin I (Qualitative)

Special Proteins

ASO

C3 Complement

C4 Complement

CRP, High Sensitive

IgG

IgM

Cardiac Markers

Creatine Kinase-MB (CK-MB)

B-type Natriuretic Peptide (BNP)

Troponin I

Troponin T

Electrolytes

Calcium, Ionized

Calcium, Total

Chloride, Cl

Magnesium (Mg)

Phosphorus (P)

Potassium (K)

Sodium, Na

Osmolality, Blood

Osmolality, Urine

4 Test Package, E3+ (Na, K, Hg,Hct)

G3+ (Ph, PCO2,PO2, HCO3, BE, SO2)

EG7 (Na, K, Ical, Hct, Ph, PCO2, TCO2, HCO3, BE, SO2, HB)

Transtubular Potassium Gradient (TTKG)

Urine

Citric Acid, 24 Hour Urine

Chloride, Urine

Creatinine Clearance, 24 Hour Urine

VMA, 24 Hour Urine

Metanephrine, 24 Hour Urine

Microalbumin/Creatinine Ratio

Total Protein, 24 Hour Urine

Urine Protein/ Creatinine Ratio (UPC)

K t/v procedure

Others

Cerebrospinal Fluid (Protein, Sugar, Magnesium, Chloride)

Other Body Fluids (Protein, Sugar, Sodium, Potassium)

Urinary Calculi Analysis (Stone Analysis)

Special Chemistry

Therapeutic Drug Monitoring

Acetaminophen/Paracetamol

Carbamazepine (Tegretol)

Cyclosporin Assay

Digoxin ( Lanoxin)

Lithium

Methotrexate

Phenobarbital (Luminal)

Phenytoin (Dilantin)

Theophylline

Valproic Acid (Depakene)

Vancomycin

Serology

Anti-Streptolysis O (ASO) Titer

C-Reactive Protein

Dengue IgG & IgM

Dengue NS1

HCG, Serum

Infectious Mononucleosis Test (Monospot Test)

Rheumatoid Arthritis: Latex Agglutination (R.F. Test)

RPR:Qualitative

Treponema Pallidum Hemaagglutination Test (TPHA)

Typhidot IgG & IgM

VDRL

Cold Agglutinins

Immunology

Alcohol/Ethanol

Allergry Testing

a. Combination of Phadiatop, Total IgE, FX5

b. Combination of Phadiatop, Total IgE

c. Panel of 10 allergens ( Choices of specific individual allergens)

d. Panel of 20 allergens

Specific / Individual Allergen Test

Dust Mite

a. D.pteronyssinus (d1)

b. D.farinae (d2)

Sea Foods

a. Crab (f23)

b. Shrimp (f24)

c. Squid (f58)

d. Blue mussel (f37)

e. Tuna (f40)

f. Fish (cod) (f3)

g. Salmon (f41)

Nuts

a. Peanut (f13)

b. Almond (f20)

c. Cashew (f202)

Dander / Epithelium

a. Cat dander (e1)

b. Dog dander (e5)

Insect

a. Cockroach (i6)

b. Mosquito (i7i)

Fruits

a. Mango (f91)

b. Orange (f33)

Trees / Grass / Weeds

a. Acacia (t19)

c. Bermuda grass (g2)

d. Johnson grass (g10)

e. Common ragweed (w1)

f. Common pigweed (w14)

Vegetables

a. Tomato (f25)

Others

a. Latex (k82)

Moulds

a. P.notatum (m1)

Poultry / Meat

a. Egg white (f1)

b. Egg yolk (f75)

c. Chicken meat (f83)

d. Pork (f26)

e. Beef (f27)

Dairy Products

a. Cheddar cheese (f81)

b. Milk (f2)

Grains

a. Wheat (f4)

b. Oat (f7)

c. Soya Bean (f14)

d. Cacao (f93)

Alpha Feto Protein

ANA

ANCA C and P

Anti DNA/Anti Ds DNA

Anti SM/RNP

Anti Ssa/Ssb

Anti-Cardiolipin (IgG & IgM)

Anti-HAV (IgG/IgM)

Anti-HBc (IgG/IgM)

Anti-HBe

Anti-HBs

Anti-HCV

Anti-Jo-1

Anti-RNP/ Anti-Ribonucleoprotein

Anti-SCL 70

B2 Glycoprotein (IgG/IgM)

B2-Microglobulin

Beta HCG

B-type Natriuretic Peptide (BNP)

CA 125 (Ovarian)

CA 15-3 (Breast)

CA 19-9 (Pancreas)

CD 4 / CD 8

CEA (Colon)

Ceruloplasmin

Cortisol

CSF IgG

C-Peptide

Cytomegalovirus (IgG/IgM)

Dheas

EBV (IgG, IgM)

Estradiol/E2

Ferritin

Folic Acid (serum folate)

Food Intolerance

Free Light Chain (Kappa & Lambda)

Follicle Stimulating Hormone (FSH)

FT3

FT4

FTA-ABS

Galactomannan

HBeAG

HBsAG

Hemoglobin Electrophoresis

Hepatitis Profile

a. HP 1 (Diagnostic)

* Anti-HAV (IgG)

* Anti-HAV (IgM)

* Anti-HBc (IgM)

* Anti-HCV

* HBsAg

b. HP 2 (HBV Diagnostic Follow-up)

* Anti-Hbe

* Anti-HBs

* HBeAg

c. HP 3 (HBV Patient Management)

* Anti-HBe

* HBeAg

* HBsAg

d. HP 4 (HBV Immune Status)

* Anti-HBc (Total)

* Anti-Hbs

e. HP 5 (HBV Panel)

* Anti-HBc (IgM)

* Anti-HBc (Total)

* Anti-HBe

* Anti-HBs

* HBeAg

* HBsAg

f. HP 6 (Complete Hepatitis Panel)

* Anti-HAV (IgG)

* Anti-HAV (IgM)

* Anti-HBc (IgM)

* Anti-HBc (Total)

* Anti-HBe

* Anti-HBs

* Anti-HCV

* HBeAg

* HBsAg

HE-4 / Human Epididymis Protein 4 (Ovarian)

Herpes Simplex Virus I (HSV I & II [IgM](IgG])

Homocysteine

H-Pylori (IgG)

Immunophenotyping (Leukemia/Lymphoma/Immunodeficiency Panel)

Immunofixation (Serum & Urine)

Insulin

L.E. Profile (DNA, ANA, Anti SM/RNP, Anti Ssa/Ssb)

Leptospiral (IgM)

Lupus Anticoagulant/ APAS Panel (APTT,KCT,DRVVT,ACA IgG/IgM)

Luteinizing Hormone (LH)

Maternal Screening ( Papp-A, PIGF, B-HCG)

Mumps IgG/IgM

NGAL/ Neutrophil Gelatinase-associated Lipocalin (Urine)

Narcotic Drugs Of Abuse

a. Amphetamines / Metamphetamines

b. Barbiturates

c. Benzodiazepines

d. Cannabinoids (Marijuana)

e. Cocaine

f. Morphine / Opiates

Procalcitonin

Progesterone

Prolactin

PSA, Free ( Prostate Specific Antigen)

PSA, Total( Prostate Specific Antigen)

Qualitative Drug Screen (Methamphenamine/Ca)

Rubella IgG/IgM

Rubeola IgG/IgM

Serum Protein Electrophoresis (SPE)

Tacrolimus/ Prograf

Testosterone

Thyroxine (T4)

TORCH Test (Titer)

a. Toxoplasma IgM/IgG

b. Rubella (IgG/IgM)

c. CMV IgM/IgG

d. HSV 1 & 2, IgG

Triiodothyronine (T3)

Thyroid Stimulating Hormone (TSH)

Transferrin

Varicella IgG/IgM

Vitamin B12

Vitamin D

Flow Cytometry (Immunophenotyping (Leukemia/Lymphoma Immunodeficiency Panel)

a. Comprehensive Leukemia (Bone Marrow or Peripheral Blood - EDTA)

* Anti-Kappa

* Anti-Lambda

* CD10

* CD117

* CD13

* CD15

* CD19

* CD20

* CD22

* CD3

* CD33

* CD34

* CD4

* CD41a

* CD5

* CD56

* CD7

* CD8

* Glycophorin-A

* HLA-DR

b. Basic Leukemia (Bone Marrow or Peripheral Blood - EDTA)

* CD10

* CD13

* CD19

* CD20

* CD22

* CD3

* CD33

* CD34

* CD5

* CD56

* CD7

* HLA-DR

c. All (Acute Lmphocytic Leukemia) (Bone Marrow or Peripheral Blood - EDTA)

* Anti-Kappa

* Anti-Lambda

* CD10

* CD13

* CD19

* CD20

* CD22

* CD3

* CD33

* CD34

* CD4

* CD5

* CD56

* CD7

* CD8

* HLA-DR

d. AML (Acute Myelocytic Leukemia) (Bone Marrow or Peripheral Blood - EDTA)

* CD10

* CD117

* CD13

* CD15

* CD19

* CD20

* CD22

* CD3

* CD33

* CD34

* CD41a

* CD5

* CD56

* CD7

* Glycophorin-A

* HLA-DR

e. Comprehensive Lymphoma (Peripheral Blood or Tissue or Body Fluids)

* Anti-Kappa

* Anti-Lambda

* CD10

* CD11c

* CD16+CD56

* CD19

* CD20

* CD2

* CD22

* CD23

* CD3

* CD4

* CD5

* CD7

* CD8

f. Minimal Residual Disease (MRD)

* CD10

* CD117

* CD13

* CD15

* CD19

* CD20

* CD22

* CD3

* CD33

* CD34

* CD5

* CD56

* CD7

* HLA-DR

g. MRD for AML

* CD10

* CD117

* CD13

* CD15

* CD19

* CD20

* CD22

* CD3

* CD33

* CD34

* CD5

* CD56

* CD7

* HLA-DR

h. MRD for T-All

* CD10

* CD13

* CD19

* CD20

* CD22

* CD3

* CD33

* CD34

* CD4

* CD5

* CD56

* CD7

* CD8

* HLA-DR

i. MRD for B-All

* Anti-Kappa

* Anti-Lambda

* CD10

* CD13

* CD19

* CD20

* CD22

* CD3

* CD33

* CD34

* CD5

* CD56

* CD7

* HLA-DR

j. Comprehensive Leukemia Panel with Lymphoma Panel

* CD20 / CD5

* CD19 / CD10

* CD19 / CD23

* CD7 / CD2

* CD3 / CD16 + CD56

* CD22 / CD11c

k. Immunodeficiency Panel 1 (T & B Cells)

* CD3

* CD19

* CD4

* CD8

* CD16 + CD56

l. Immunodeficiency Panel 2 (T Cells)

* CD4

* CD8

m. Immunodeficiency Panel 3 (NK Cells)

* CD3

* CD16 + CD56

n. Immunodeficiency Panel 4 (B Cells)

* CD3

* CD19

Microbiology

Culture

AFB Culture (Bactec)

Anaerobic Culture

Blood Culture and Sensitivity

Fungal Culture

Mycobacterial Blood Culture

Neisseria gonorrhea: Culture

Routine: Any other specimen with Gram Stain

Routine: Throat Swab, Nasotracheal secretions, Urine, Catheter tips (w/o G/S)

Stool Culture

Stool culture for V. Cholera

Microscopic

AFB Smear

Giemsa Stain

Gram Stain

India Ink

KOH Preparation

Microscopic Examination for Crystals (Body Fluids)

Modified AFB Smear

Wet Mount Preparation (Fresh Smear)

Others

Chlamydiazyme Test

Clostridium Difficile Toxin A II (CDA 2)

Cryptococcal Antigen Latex Agglutination System (CALAS)

E-test ESBL (Extended Spectrum Beta Lactamase)

Group B Strep

Latex agglutination test for bacterial antigens (LBAT)/Phadebact

Legionella Ag Rapid Test (Urine)

MIC (Minimum Inhibitory Concentration)/ E-test (Extended spectrum beta-lactamase)

Rapid Group A Strep

Rapid Urease Test (Clotest)

Streptococcus Pneumoniae Antigen

Molecular Diagnostics

Cytomegalovirus -DNA/PCR (CMV)

Dengue PCR

Epstein-Barr Virus - PCR (EBV)

Epidermal Growth Factor Receptor (EGFR)

Enterovirus

Hepatitis B Vicrus - PCR (HBV)

Hepatitis C Virus-RNA-PCR (HCV)

HLA B27

HLA Typing PCR/ Tissue Typing/ DNA Typing / Luminex High Resolution

Human Papilloma Virus-DNA (HPV)

Herpes Simplex Virus-PCR (HSV)

Human Immunodeficiency Virus-1 (VCT)- 1 Viral Load (HIV-1)

Japanese B Encephalitis

Legionella- PCR

Mycobacterium Tuberculosis - Multiplex-PCR (MTB)

Mycobacterium Tuberculosis - RIF-GeneXpert (MTB

Pneumocytis Carinii Pneumonia- PCR (PCP)

Varicella Zoster Virus - PCR (VZV)

Viral Meningits Panel by PCR

A. Enterovirus

B. Herpes Simplex Virus (HSV)

C. Epstein-Barr Virus (EBV)

D. Japanese B Encephalitis

E. Varicella Zoster Virus

Histopath

Autopsy

a. Complete - Including brain

b. Limited - Brain not included

Cell Block

Cytology

a. Cervico-vaginal w/ or w/o Maturation Index

a.a Conventional

a.b Thin Prep (Liquid Based)

b. Non-Gyne ( Body fluids)

Cytospin

FNAB (Smear only)

FNAB (UT/CT Guided)

Gross Examination

Histopath Slide (Duplicate slides)

ImmunoHistoChemical Stains Available

ALK-1

Hbme

Sma (Smooth -muscle Actin)

Idh-1

M-Cea

Melan-A

Myogenin

P504S

P63 Protein

Bcl2

Bcl6

BER-EP4

CA19-9

Caldesmon

Calretinin

CAM 5.2

CD 117/ C KIT

CD10

CD138

CD15

CD1a

CD20 - B cell (Cluster Differentiation 20)

CD21

CD23

CD3 / T-cell

CD30 - Ki - 1 Antigen (Cluster Differentiation 30)

CD34

CD38

CD45 - LCA (Leucocyte Common Antigen)

CD45 RO - T cell

CD5

CD56

CD68

CD79A

CD99

Chromogranin A

CK 20 (Cytokeratin 20)

CK 7 (Cytokeratin 7)

CK19

CK5/6

Cyclin D1

Cytokeratin

Cytokeratin HMW (High Molecular Weight)

Desmin

E-Cadherin

E-Cadherin

EMA (Epithelial Membrane Antigen)

Estrogen Receptor

GATA3

GCDFP 15

GFAP (Glial Fibrillary Acidic Protein)

HAS

Hepatocyte (Hepar)

HER 2 (C-ErbB-2 Oncoprotien)

HMB45

INI-1

Kappa Light Chain

Ki-67

Lambda Light Chain

Mammaglobin

Mesothelial Cells

MSA

MUM-1

Muscle Actin

Myeloperoxidase / MPO

Neurofilament

NSE (Neuron Specific Enolase)

P16

P53

P53

PAX5

Progesterone Receptor

PSA (Prostate Specific Antigen)

S-100

SMMHC (Smooth Muscle Myosin Heavy Chain)

Synaptophysin

TDT

TTF-1 (Thyroid Transcription Factor)

Vimentin

Intra Operative Consultation or Frozen Section

Packages

a. Breast Package 1 (Radical, ER, PR)

b. Breast Package 2 (Radical, ER, PR, Her-2)

c. Prostate Panel

Routine Histopath (H & E)

a. Bone Marrow (Wright's, Giemsa, Reticulin, Prussian blue package)

b. Large Specimen

c. Medium Specimen

d. Radical Resection

e. Small-Diagnostic

f. Small Specimen

g. Small w/ Decalcification

Special Stain

a. Grams Stain

b. Grocotts

c. PAS

d. Reticulin

e. Mucicarmine

f. Ziehl Nielsen Acid Fast

g. Masson-Goldner Trichrome Stain

Renal Biopsy (Light Microscopy & Immunoflourescence)

Her2 Dual In-Situ Hybridization DNA Probe Cocktail Assay

Slide Review

 

Our Team

Dr. Elizabeth Y. Arcellana-Nuqui - Chair, Department of Laboratory Medicine and Pathology

Pathology

Dr. Agustina D. Abelardo

Dr. Elizabeth Ann S. Alcazaren

Dr. Elizabeth Y. Arcellana-Nuqui

Dr. Jose M. Carnate, Jr.

Dr. Gregorio B. Cortez III

Dr. Sarah Jane L. Datay-Lim

Dr. Rouchelle D. Dela Cruz

Blood Bank & Transfusion Services

Dr. Pedrito Y. Tagayuna

Forensic Pathology

Dr. Raquel dR. Fortun

Dr. Maria Cecilia F. Lim

Hematopathology

Dr. Alejandro E. Arevalo

Nephropathology

Dr. Alan T. Koa

Neuropathology

Dr. Edwin L. Munoz

Orthopedic Pathology

Dr. Carmelita V. Navarro

Laboratory Quality and Safety

Dr. Sarah Jane L. Datay-Lim

Ma. Lourdes L. Gatbonton – Senior Manager, Department of Laboratory Medicine and Pathology